Annotation of Full-Length, Intact L1 Elements
What is L1Base?

L1Base is a dedicated database containing putatively active LINE-1 (L1) insertions residing in human and rodent genomes: a) intact in the two ORFs, full length L1s (FLI-L1s) and b) L1s with intact ORF2 but disrupted ORF1 (ORF2-L1s). In addition, due to their regulatory potential, the full length (>6000bp) non-intact L1s (FLnI-L1s) were also included in the database.

If you are experimentalists and you seek a bioinformatics expertise on analysis of LINE-1 elements, do not hesitate to send us an email!

If you are using data stored in L1Base for your research please cite L1Base: from functional annotation to prediction of active LINE-1 elements Nucl. Acids Res. 2004 33: D498-D500; doi:10.1093/nar/gki044




Tomasz Zemojtel, Institute for Molecular Genetics, Max-Plack Institute Berlin
Tobias Penzkofer, Department of Bioinformatics, University of Würzburg